The most common adverse reactions (occurring at >/= to 5% and at least twice the placebo rate for any dose) were somnolence, decreased appetite, fatigue, nausea, vomiting, insomnia, and irritability.2
Ask your patients about their medical conditions, including if they:
- If they have or their family has a history of suicide, bipolar disorder, depression, mania or hypomania
- Have blood pressure or heart rate problems
- Have severe kidney disease or dysfunction. Their dose of Qelbree and/or other medicines may need to be reduced3
- Have liver problems
- Are pregnant or plan on becoming pregnant
- Are breastfeeding or plan to breastfeed
Ask your patients about all the medicines they take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Taking Qelbree with certain other medicines may cause side effects or affect how well they work.
Especially ask if your patients take:
- Asthma medicines including theophylline
- Anti-depression medicines including MAOIs (monoamine oxidase inhibitors)
- Medicines metabolized by liver enzymes CYP1A2, 2D6 or 3A4
Do not administer Qelbree if patients are allergic to viloxazine or any of the other ingredients in Qelbree. See the end of the Medication Guide for a complete list of ingredients in Qelbree.
Do not administer Qelbree if patients also take a medicine called a monoamine oxidase inhibitor (e.g., isocarboxazid, phenelzine, selegiline, tranylcypromine).
Store Qelbree capsules at room temperature 77°F (25°C). Keep Qelbree and all medicines out of reach of children.1
Qelbree can be taken with or without food, whole or sprinkled entire contents onto a teaspoonful of applesauce and all consumed within 2 hours. Capsules and their contents should not be cut, crushed, chewed.1
100 mg: yellow, opaque body and cap (printed “SPN” on the cap, “100” on the body)1
150 mg: lavender, opaque body and cap (printed “SPN” on the cap, “150” on the body)1